Product ID:VALINOMYCIN CRYSTALLINE, V0627
MSDS Date:07/01/1999
FSC:6550
NIIN:00N021631
Status Code:A
MSDS Number: CJRLY

Emergency Phone: 314-771-5765

Info Phone: 314-771-5765

Cage: 21076

Telephone: 314-771-5765

Cage: 21076

(ORAL,RAT) 4 MG/KG.

CAS: 2001-95-8

RTECS: YV9468000

LD50 LC50 Mixture:SEE INGREDIENT & TOXICOLOGICAL INFO.
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:ACUTE: MAY BE FATAL IF INHALED,
SWALLOWED OR ABSORBED THROUGH SKIN. MAY CAUSE IRRITATION. MAY CAUSE
CONVULSIONS. TARGET ORGAN(S): HEART, PERIPHERAL NERVOUS SYSTEM,
CENTRAL NERVOUS SYSTEM. TARGET ORGAN DATA: BEHAVIORAL (TREMOR;
CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD); NUTRITIONAL AND GROSS
METABOLIC (WEIGHT LOSS OR DECREASED WEIGHT GAIN).
Effects of Overexposure:SEE HEALTH HAZARDS.

First Aid:EYES: IMMEDIATELY FLUSH WITH COPIOUS AMOUNTS OF WATER FOR AT
LEAST 15 MINUTES. SKIN: IMMEDIATELY FLUSH WITH COPIOUS AMOUNTS OF
WATER FOR AT LEAST 15 MINUTES WHILE REMOVING CONTAMINATED CLOTHING
AND SH OES. WASH CONTAMINATED CLOTHING BEFORE REUSE. INHALATION:
REMOVE TO FRESH AIR. IF NOT BREATHING GIVE ARTIFICIAL RESPIRATION.
IF BREATHING IS DIFFICULT, GIVE OXYGEN. INGESTION: WASH OUT MOUTH
WITH WATE R PROVIDED PERSON IS CONSCIOUS. CALL MD.

Extinguishing Media:WATER SPRAY, CARBON DIOXIDE, DRY CHEMICAL POWDER OR
APPROPRIATE FOAM.
Fire Fighting Procedures:USE NIOSH APPROVED SCBA AND FULL PROTECTIVE
EQUIPMENT .
Unusual Fire/Explosion Hazard:EMITS TOXIC FUMES UNDER FIRE CONDITIONS.

Spill Release Procedures:EVACUATE AREA. WEAR NIOSH APPROVED
SELF-CONTAINED BREATHING APPARATUS, RUBBER BOOTS AND HEAVY RUBBER
GLOVES. SWEEP UP, PLACE IN A BAG AND HOLD FOR WASTE DISPOSAL. AVOID
RAISING DUST. VENTILATE AREA AN D WASH SPILL SITE AFTER MATERIAL
PICKUP IS COMPLETE.

Handling and Storage Precautions:DO NOT BREATHE DUST. DO NOT GET IN
EYES, ON SKIN, ON CLOTHING. AVOID PROLONGED OR REPEATED EXPOSURE.
READILY ABSORBED THROUGH SKIN. HIGHLY TOXIC. KEEP TIGHTLY CLOSED.
REFRIGERATE.
Other Precautions:VERY TOXIC BY INHALATION, IN CONTACT WITH SKIN AND IF
SWALLOWED. IN CASE OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK MEDICAL
ADVICE IMMEDIATELY (SHOW THE LABEL WHERE POSSIBLE).

Respiratory Protection:WEAR APPROPRIATE NIOSH APPROVED RESPIRATOR.
Ventilation:USE ONLY IN A CHEMICAL FUME HOOD.
Protective Gloves:CHEMICAL-RESISTANT GLOVES.
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES & FULL LENGTH
FACESHIELD .
Other Protective Equipment:EYE WASH & DELUGE SHOWER MEETING ANSI DESIGN
CRITERIA . WEAR SUITABLE OTHER PROTECTIVE CLOTHING.
Work Hygienic Practices:WASH THOROUGHLY AFTER HANDLING.
Supplemental Safety and Health

Melt/Freeze Pt:>187.C, 368.6F
M.P/F.P Text:187C TO 188C
Solubility in Water:INSOLUBLE
Appearance and Odor:WHITE POWDER.

Stability Indicator/Materials to Avoid:YES
STRONG OXIDIZING AGENTS.
Hazardous Decomposition Products:TOXIC FUMES OF: CARBON MONOXIDE,
CARBON DIOXIDE.

Waste Disposal Methods:DISSOLVE OR MIX THE MATERIAL WITH A COMBUSTIBLE
SOLVENT AND BURN IN A CHEMICAL INCINERATOR EQUIPPED WITH AN
AFTERBURNER AND SCRUBBER. OBSERVE ALL FEDERAL, STATE AND LOCAL
ENVIRONMENTAL REGULATIONS.

Toxicological Information:TO THE BEST OF MANUFACTURER'S KNOWLEDGE, THE
CHEMICAL, PHYSICAL AND TOXICOLOGICAL PROPERTIES HAVE NOT BEEN
THOROUGHLY INVESTIGATED. TOXICITY DATA: LD50:(ORAL,RAT) 4 MG/KG;
LD50:(IPR,RAT) 800 UG/KG; LD 50:(SKN,RBT) 5 MG/KG - DCTODJ
8,451,1985. LD50:(ORAL,MUS) 2500 UG/KG - 85ERAY 1,325,1978.
LD50:(IPR,MUS) 390 UG/KG - NCISP* JAN1986. LD50:(SCU,MUS) 4140
UG/KG - ANTCAO 12,482,1962. LD50:(IVN,MUS) 180 UG/KG - CNREA8
46,5518,1986. ONLY SELECTED REGISTRY OF TOXIC EFFECTS OF CHEMICAL
SUBSTANCES (RTECS) DATA IS PRESENTED HERE. SEE ACTUAL ENTRY IN
RTECS FOR COMPLETE INFORMATION.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.

Ecological:DATA NOT YET AVAILABLE.

Transport Information:CONTACT SIGMA CHEMICAL COMPANY FOR TRANSPORTATION
INFORMATION.

Federal Regulatory Information:EUROPEAN INFORMATION: VERY TOXIC; R
26/27/28 - VERY TOXIC BY INHALATION, IN CONTACT WITH SKIN AND IF
SWALLOWED; S 45 - IN CASE OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK
MEDICAL ADVICE IMMEDIATELY (SHOW LABEL WHERE POSSIBLE); S 36/37/39
- WEAR SUITABLE PROTECTIVE CLOTHING, GLOVES AND EYE/FACE
PROTECTION; S 22 - DO NOT BREATHE DUST. -- REVIEWS, STANDARDS AND
REGULATIONS: OEL=MAK. EPA TSCA SECTION 8(B) CHEMICAL INVENTORY.